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IMF-070-01-0001-en	Why is paediatric medicine grounded in development rather than scaled-down adult physiology?	Organ systems mature at different rates, body composition changes, developmental tasks alter behaviour, and disease can disrupt future growth as well as current function.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0002-en	When does crossing centiles in infancy call for evaluation rather than reassurance?	Crossing can be normal catch-up or catch-down growth, but sustained downward crossing, discordance among weight, length, and head growth, or accompanying symptoms requires evaluation.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0003-en	How does the pattern of weight versus length help distinguish inadequate intake from endocrine disease?	With inadequate intake or absorption, weight often falls before length, whereas endocrine disorders may reduce linear growth while weight is preserved or increased.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0004-en	What do bone age and mid-parental height each contribute to growth assessment, and what limits them?	Bone age estimates skeletal maturation to separate delayed maturation from impaired growth potential but varies with technique and population; mid-parental height is a broad familial target, not a guarantee.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0005-en	How does adrenarche relate to the central onset of puberty?	Puberty begins when hypothalamic gonadotropin-releasing hormone pulsatility reactivates, driving gonadotropin and gonadal steroid production; adrenarche is partly independent and produces pubic or axillary hair and body odour.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0006-en	Why are pubertal stages assessed by physical development rather than by age alone?	Pubertal timing varies with genetics, nutrition, body composition, chronic illness, and population, so age alone does not define the stage.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0007-en	If milestones are distributions rather than deadlines, what matters besides the age a skill is acquired?	The sequence and quality of skills, the opportunities to practise, and any regression are as important as the age of acquisition.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0008-en	Why can persistent asymmetry, abnormal tone, or early hand preference indicate neurological disease?	Motor development depends on the central and peripheral nervous systems, with cortical control gradually inhibiting primitive reflexes, so these signs may reflect disease in that pathway.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0009-en	Why is hearing assessment essential in speech delay even when caregivers believe hearing is normal?	Language development requires hearing alongside social interaction, cognition, motor planning, and exposure to comprehensible language, so hearing must be assessed rather than assumed.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0010-en	Why is bilingualism not itself a cause of language delay, and which features do change the differential?	Bilingual children distribute vocabulary across languages and are not inherently delayed; loss of language, absent social reciprocity, poor response to sound, or failure to use gesture change the differential.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0011-en	Why should no single behaviour be taken as proof of a specific family circumstance?	Behaviour is shaped by normal temperament as well as deprivation, inconsistent safety, caregiver mental illness, trauma, and neurodevelopmental differences, so one behaviour cannot identify its cause.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0012-en	How does the developmental timing of adolescent reward sensitivity explain risk-taking, and what does it not justify?	Reward sensitivity and social salience develop earlier than full regulatory control, favouring exploration and risk-taking; this is not an incapacity to reason or grounds to exclude adolescents from decisions.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0013-en	What distinguishes developmental delay, intellectual disability, and a specific developmental disorder?	Delay is significant lag in one or more domains in young children; intellectual disability limits intellectual and adaptive function with developmental onset; specific disorders affect one area without global impairment.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0014-en	Why is regression always important, and what should be clarified when it is reported?	Loss of acquired skills can reflect epileptic encephalopathy, neurodegeneration, metabolic or inflammatory brain disease, or severe psychosocial disruption; clarify the skill lost, the settings, and sensory, motor, or engagement change.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0015-en	How can a child appear to regress without an underlying disease process?	Apparent loss of skills can occur when developmental demands exceed the child's capacity, which is why the lost skill and its context must be clarified.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0016-en	Why should an autism diagnosis map strengths and needs, and why must it not be used to explain every symptom?	Presentation varies with language, cognition, sex, culture, compensatory strategies, and support, so diagnosis should not reduce a person to deficits, and other behavioural or medical symptoms still need their own explanation.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0017-en	Why must apparent attention-deficit hyperactivity disorder be interpreted against developmental level and context?	Sleep disorder, anxiety, learning difficulty, trauma, hearing or vision problems, absence seizures, and environmental mismatch can mimic or coexist with it.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0018-en	Why can infants decompensate quickly with airway illness, and what does bradycardia signify in a sick infant?	High oxygen demand, compliant chest walls, small airways, and limited reserve mean a small loss of radius sharply raises resistance and work causes fatigue; bradycardia often reflects hypoxia and is a pre-arrest sign.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0019-en	Why are infants prone both to rapid dehydration and to hyponatraemia from excess hypotonic fluid?	They have a higher body water proportion, immature renal concentrating ability, and rapid fluid turnover, so losses dehydrate them quickly while excessive hypotonic fluid can lower sodium.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0020-en	Why is neonatal hypothermia a concern beyond exposure, and why are neonates prone to hypoglycaemia?	Large surface area, limited insulation, and immature control make thermoregulation inefficient, and hypothermia can signal sepsis; limited glycogen stores allow hypoglycaemia during illness or feeding difficulty.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0021-en	Why is fever height a poor guide to bacterial infection, particularly in very young infants?	Height alone does not separate bacterial from viral disease; risk depends on age, appearance, immune status, focal signs, and physiology, and very young infants may have invasive infection with low or normal temperature.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0022-en	How do stridor, wheeze, and stertor localise the site of airway obstruction?	Stridor indicates upper-airway narrowing, wheeze usually reflects intrathoracic airway obstruction, and stertor arises from the nasopharynx.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0023-en	What does bilious vomiting suggest compared with projectile non-bilious vomiting in early infancy?	Bilious green vomiting suggests obstruction distal to the ampulla until proven otherwise, whereas projectile non-bilious vomiting in early infancy can indicate pyloric stenosis.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending
IMF-070-01-0024-en	Why do adolescents need confidential time, and why must its limits be explained?	Privacy supports disclosure about home, education, eating, substances, sexuality, mood, and safety, but safeguarding concerns may require proportionate information sharing.	Integrated Medical Foundations; chapter 70, TTS module 1; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 57a482514b2ddafa1cb35d8a22feaf27d34f4149f37bb4986ae257171a251189; editorial review pending	imf lang::en chapter::070 module::070-01 review::pending