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IMF-010-02-0001-en	Why is arterial hypotension neither necessary nor sufficient for shock?	A young person can preserve pressure by intense vasoconstriction despite major blood loss, while a chronically low pressure can be tolerated when perfusion is stable.	Integrated Medical Foundations; chapter 10, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 6cda2c6cc7dce26be5510625183e16ae16f44dd65378b2caec908f04371fc714; editorial review pending	imf lang::en chapter::010 module::010-02 review::pending
IMF-010-02-0002-en	Name the haemodynamic phenotypes the bedside assessment tries to identify.	Preload failure, pump failure, vasoplegia, obstruction, and microcirculatory failure, with mixed forms expected.	Integrated Medical Foundations; chapter 10, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 6cda2c6cc7dce26be5510625183e16ae16f44dd65378b2caec908f04371fc714; editorial review pending	imf lang::en chapter::010 module::010-02 review::pending
IMF-010-02-0003-en	Why does a high venous oxygen saturation not guarantee adequate perfusion?	Distributive shunting, impaired extraction, or mitochondrial dysfunction can leave oxygen in venous blood while some tissue is starved.	Integrated Medical Foundations; chapter 10, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 6cda2c6cc7dce26be5510625183e16ae16f44dd65378b2caec908f04371fc714; editorial review pending	imf lang::en chapter::010 module::010-02 review::pending
IMF-010-02-0004-en	What can go wrong as oxygen debt is repaid by restoring flow and oxygen content?	Reperfusion can expose tissue injury and wash accumulated metabolites into the circulation, while temperature, glucose, calcium, acidity, and coagulation interact with the transition.	Integrated Medical Foundations; chapter 10, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 6cda2c6cc7dce26be5510625183e16ae16f44dd65378b2caec908f04371fc714; editorial review pending	imf lang::en chapter::010 module::010-02 review::pending
IMF-010-02-0005-en	When is blind fluid loading the wrong response to a rising lactate?	When the driver is cardiogenic congestion, seizure, hepatic failure, or beta-adrenergic stimulation.	Integrated Medical Foundations; chapter 10, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 6cda2c6cc7dce26be5510625183e16ae16f44dd65378b2caec908f04371fc714; editorial review pending	imf lang::en chapter::010 module::010-02 review::pending
IMF-010-02-0006-en	What does fluid responsiveness mean, and what does it fail to prove?	It means stroke volume is likely to rise after preload increases; it does not prove that fluid is the best treatment or that tissue perfusion will improve.	Integrated Medical Foundations; chapter 10, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 6cda2c6cc7dce26be5510625183e16ae16f44dd65378b2caec908f04371fc714; editorial review pending	imf lang::en chapter::010 module::010-02 review::pending
IMF-010-02-0007-en	Why do static filling pressures predict fluid response poorly, and what is used instead?	Ventricular compliance varies, so dynamic tests using a reversible preload change are used, such as passive leg raising assessed with a real-time output measure.	Integrated Medical Foundations; chapter 10, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 6cda2c6cc7dce26be5510625183e16ae16f44dd65378b2caec908f04371fc714; editorial review pending	imf lang::en chapter::010 module::010-02 review::pending
IMF-010-02-0008-en	What counts as a convincing response to a fluid challenge, and what does not?	Improved stroke volume or perfusion with acceptable filling pressure is convincing; a transient blood-pressure rise alone can reflect vascular tone or measurement noise.	Integrated Medical Foundations; chapter 10, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 6cda2c6cc7dce26be5510625183e16ae16f44dd65378b2caec908f04371fc714; editorial review pending	imf lang::en chapter::010 module::010-02 review::pending
IMF-010-02-0009-en	Why can raising systemic resistance with a vasopressor reduce flow?	Mean arterial pressure approximates cardiac output times systemic resistance, so when the ventricle cannot overcome the new load, output falls as resistance rises.	Integrated Medical Foundations; chapter 10, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 6cda2c6cc7dce26be5510625183e16ae16f44dd65378b2caec908f04371fc714; editorial review pending	imf lang::en chapter::010 module::010-02 review::pending
IMF-010-02-0010-en	How does noradrenaline (norepinephrine) improve preload as well as arterial pressure?	Its venoconstriction recruits unstressed volume, which raises venous return in addition to arterial tone.	Integrated Medical Foundations; chapter 10, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 6cda2c6cc7dce26be5510625183e16ae16f44dd65378b2caec908f04371fc714; editorial review pending	imf lang::en chapter::010 module::010-02 review::pending
IMF-010-02-0011-en	Trace the spiral that follows an acute rise in right-ventricular afterload.	The right ventricle dilates, wall stress and oxygen demand rise, tricuspid regurgitation worsens, and the septum shifts leftward, reducing left-ventricular filling.	Integrated Medical Foundations; chapter 10, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 6cda2c6cc7dce26be5510625183e16ae16f44dd65378b2caec908f04371fc714; editorial review pending	imf lang::en chapter::010 module::010-02 review::pending
IMF-010-02-0012-en	What should escalating vasoactive doses prompt a search for?	Ongoing bleeding, unrelieved obstruction, inadequate source control, adrenal failure, severe acidosis, occult pump dysfunction, drug effect, or measurement error.	Integrated Medical Foundations; chapter 10, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: 6cda2c6cc7dce26be5510625183e16ae16f44dd65378b2caec908f04371fc714; editorial review pending	imf lang::en chapter::010 module::010-02 review::pending