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IMF-006-02-0001-en	State Bayes' principle in the form used at the bedside.	Prior odds multiplied by the likelihood ratio of the new evidence gives posterior odds.	Integrated Medical Foundations; chapter 6, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: dba09072c4d938db627ddcbc2607b770711d3ff15ae1b730fbf7f9762875162d; editorial review pending	imf lang::en chapter::006 module::006-02 review::pending
IMF-006-02-0002-en	What clinical question do predictive values answer that sensitivity and specificity do not?	Given this result, how likely is disease; sensitivity and specificity are conditional on disease status instead.	Integrated Medical Foundations; chapter 6, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: dba09072c4d938db627ddcbc2607b770711d3ff15ae1b730fbf7f9762875162d; editorial review pending	imf lang::en chapter::006 module::006-02 review::pending
IMF-006-02-0003-en	Name four things that change a likelihood ratio, so that it is not a fixed property of a test.	Disease spectrum, test threshold, operator skill, and timing; the definition of the reference standard also changes it.	Integrated Medical Foundations; chapter 6, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: dba09072c4d938db627ddcbc2607b770711d3ff15ae1b730fbf7f9762875162d; editorial review pending	imf lang::en chapter::006 module::006-02 review::pending
IMF-006-02-0004-en	Why does multiplying the likelihood ratios of several inflammatory markers exaggerate certainty?	They respond to related biology, so they are correlated rather than independent pieces of evidence.	Integrated Medical Foundations; chapter 6, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: dba09072c4d938db627ddcbc2607b770711d3ff15ae1b730fbf7f9762875162d; editorial review pending	imf lang::en chapter::006 module::006-02 review::pending
IMF-006-02-0005-en	Distinguish the testing threshold from the treatment threshold.	Below the testing threshold investigation harms more than it helps; above the treatment threshold action is justified without waiting for a test.	Integrated Medical Foundations; chapter 6, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: dba09072c4d938db627ddcbc2607b770711d3ff15ae1b730fbf7f9762875162d; editorial review pending	imf lang::en chapter::006 module::006-02 review::pending
IMF-006-02-0006-en	Which two features of the clinical situation move a decision threshold?	The stakes, since a dangerous rapidly treatable disease justifies investigation at low probability, and the reliability of follow-up.	Integrated Medical Foundations; chapter 6, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: dba09072c4d938db627ddcbc2607b770711d3ff15ae1b730fbf7f9762875162d; editorial review pending	imf lang::en chapter::006 module::006-02 review::pending
IMF-006-02-0007-en	Give two ways empirical treatment degrades later diagnostic evidence.	Antimicrobials can sterilise cultures and glucocorticoids can suppress inflammatory findings.	Integrated Medical Foundations; chapter 6, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: dba09072c4d938db627ddcbc2607b770711d3ff15ae1b730fbf7f9762875162d; editorial review pending	imf lang::en chapter::006 module::006-02 review::pending
IMF-006-02-0008-en	What should be stated before ordering a test, so that the test carries information?	The question, the result expected under each leading diagnosis, and which decision each possible result would change.	Integrated Medical Foundations; chapter 6, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: dba09072c4d938db627ddcbc2607b770711d3ff15ae1b730fbf7f9762875162d; editorial review pending	imf lang::en chapter::006 module::006-02 review::pending
IMF-006-02-0009-en	What are semantic qualifiers, and what do they do to a case?	Contrasting descriptors such as acute against chronic or focal against diffuse; they compress many observations into a form that activates useful illness patterns.	Integrated Medical Foundations; chapter 6, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: dba09072c4d938db627ddcbc2607b770711d3ff15ae1b730fbf7f9762875162d; editorial review pending	imf lang::en chapter::006 module::006-02 review::pending
IMF-006-02-0010-en	What should be listed deliberately after forming a problem representation?	The findings the representation does not explain, since compression can discard an atypical feature, a complication, or a second independent problem.	Integrated Medical Foundations; chapter 6, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: dba09072c4d938db627ddcbc2607b770711d3ff15ae1b730fbf7f9762875162d; editorial review pending	imf lang::en chapter::006 module::006-02 review::pending
IMF-006-02-0011-en	Distinguish overdiagnosis from a false positive.	Overdiagnosis correctly identifies a condition that would never have caused symptoms or harm in that person's lifetime; a false positive is simply an incorrect result.	Integrated Medical Foundations; chapter 6, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: dba09072c4d938db627ddcbc2607b770711d3ff15ae1b730fbf7f9762875162d; editorial review pending	imf lang::en chapter::006 module::006-02 review::pending
IMF-006-02-0012-en	What is diagnostic overshadowing, and what is the practical countermeasure?	Incorrectly explaining symptoms by an existing psychiatric illness, disability, obesity, age or known diagnosis; rechecking the physical and medication causes of the change.	Integrated Medical Foundations; chapter 6, TTS module 2; https://theisegoria.github.io/medical-textbook/integrated-medical-foundations-expanded-english.md; module SHA256 at export: dba09072c4d938db627ddcbc2607b770711d3ff15ae1b730fbf7f9762875162d; editorial review pending	imf lang::en chapter::006 module::006-02 review::pending